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PTPH1 dephosphorylates and cooperates with p38γ MAPK to increase Ras oncogenesis through PDZ-mediated interaction

Protein phosphatases are believed to coordinate with kinases to execute biological functions and examples of such integrated activities however are still missing. In this report, we have identified PTPH1 (protein tyrosine phosphatase H1) as a specific phosphatase for p38γ MAPK (mitogen-activated pro...

詳細記述

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書誌詳細
主要な著者: Hou, Song-Wang, Zhi, Hui-Ying, Pohl, Nicole, Loesch, Mathew, Qi, Xiao-Mei, Li, Rong-Shan, Basir, Zainab, Chen, Guan
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848905/
https://ncbi.nlm.nih.gov/pubmed/20332238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3229
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