Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

We investigated why the cerebrospinal fluid (CSF) concentrations of Aβ42 are lower in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients. Because Aβ38/42 and Aβ40/43 are distinct product/precursor pairs, these four species in the CSF together should faithfully reflect the sta...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kakuda, Nobuto, Shoji, Mikio, Arai, Hiroyuki, Furukawa, Katsutoshi, Ikeuchi, Takeshi, Akazawa, Kohei, Takami, Mako, Hatsuta, Hiroyuki, Murayama, Shigeo, Hashimoto, Yasuhiro, Miyajima, Masakazu, Arai, Hajime, Nagashima, Yu, Yamaguchi, Haruyasu, Kuwano, Ryozo, Nagaike, Kazuhiro, Ihara, Yasuo
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376855/
https://ncbi.nlm.nih.gov/pubmed/22354516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200214
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky