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Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease
We investigated why the cerebrospinal fluid (CSF) concentrations of Aβ42 are lower in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients. Because Aβ38/42 and Aβ40/43 are distinct product/precursor pairs, these four species in the CSF together should faithfully reflect the sta...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
WILEY-VCH Verlag
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376855/ https://ncbi.nlm.nih.gov/pubmed/22354516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200214 |
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