Chargement en cours...
Concerted functions of HDAC1 and microRNA-574-5p repress alternatively spliced ceramide synthase 1 expression in human cancer cells
Histone deacetylases (HDACs) and microRNAs (miRs) have pro-survival roles, but the mechanism behind this is unclear. Repression of ceramide synthase 1 (CerS1), altering C(18)-ceramide generation, was linked to drug resistance and metastasis. Here we report that the CerS1 promoter was repressed by HD...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376837/ https://ncbi.nlm.nih.gov/pubmed/22180294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100189 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|