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Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

Sphingolipids have emerged as bioeffector molecules, controlling various aspects of cell growth and proliferation in cancer, which is becoming the deadliest disease in the world. These lipid molecules have also been implicated in the mechanism of action of cancer chemotherapeutics. Ceramide, the cen...

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Detalhes bibliográficos
Main Authors: Ponnusamy, Suriyan, Meyers-Needham, Marisa, Senkal, Can E, Saddoughi, Sahar A, Sentelle, David, Selvam, Shanmugam Panneer, Salas, Arelis, Ogretmen, Besim
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071292/
https://ncbi.nlm.nih.gov/pubmed/21062159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.10.116
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