Homo-dimerization of the PAS-B Domains of Hypoxia-Inducible Factors

The Per-Arnt-Sim (PAS) domains of hypoxia-inducible transcription factors (HIF) mediate heterodimer formation between the HIF-α forms that are induced in the event of cellular hypoxia and the constitutive HIF-β variants. Previous efforts towards structural characterization of the HIF-1α PAS domains...

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Hauptverfasser: Zhu, Jing, Martinez-Yamout, Maria, Cardoso, Rosa, Yan, Jiangli, Love, Robert A., Grodsky, Neil, Brooun, Alexei, Dyson, H. Jane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376167/
https://ncbi.nlm.nih.gov/pubmed/22424208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300525n
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