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Homo-dimerization of the PAS-B Domains of Hypoxia-Inducible Factors
The Per-Arnt-Sim (PAS) domains of hypoxia-inducible transcription factors (HIF) mediate heterodimer formation between the HIF-α forms that are induced in the event of cellular hypoxia and the constitutive HIF-β variants. Previous efforts towards structural characterization of the HIF-1α PAS domains...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376167/ https://ncbi.nlm.nih.gov/pubmed/22424208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300525n |
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