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Mapping the Interactions of the p53 Transactivation Domain with the KIX domain of CBP
Molecular interactions between the tumor suppressor p53 and the transcriptional coactivators CBP/p300 are critical for the regulation of p53 transactivation and stability. The transactivation domain (TAD) of p53 binds directly to several CBP/p300 domains (TAZ1, TAZ2, NCBD, and KIX). Here we map the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765525/ https://ncbi.nlm.nih.gov/pubmed/19220000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802055v |
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