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DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway
DJ-1, which is linked to recessively inherited Parkinson's disease when mutated, is a multi-functional protein with anti-oxidant and transcription regulatory activities. However, the mechanism(s) through which DJ-1 and the genes it regulates provide neuroprotection is not fully understood. Here...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373246/ https://ncbi.nlm.nih.gov/pubmed/22492997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds131 |
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