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Repression of α-synuclein expression and toxicity by microRNA-7
α-Synuclein is a key protein in Parkinson's disease (PD) because it accumulates as fibrillar aggregates in pathologic hallmark features in affected brain regions, most notably in nigral dopaminergic neurons. Intraneuronal levels of this protein appear critical in mediating its toxicity, because...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722353/ https://ncbi.nlm.nih.gov/pubmed/19628698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906277106 |
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