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MicroRNA-7 facilitates the degradation of alpha-Synuclein and its aggregates by promoting autophagy
Alpha-Synuclein (α-Syn) is an important protein in the pathogenesis of Parkinson disease (PD) as it accumulates as fibrillar inclusions in affected brain regions including dopaminergic neurons in the substantia nigra. Elevated levels of α-Syn seem to be crucial in mediating its toxicity. Thus, detai...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Neurosci Lett |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990033/ https://ncbi.nlm.nih.gov/pubmed/29738845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.05.009 |
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