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MicroRNA-7 Regulates the Function of Mitochondrial Permeability Transition Pore by Targeting VDAC1 Expression

Mitochondrial dysfunction is one of the major contributors to neurodegenerative disorders including Parkinson disease. The mitochondrial permeability transition pore is a protein complex located on the mitochondrial membrane. Under cellular stress, the pore opens, increasing the release of pro-apopt...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chaudhuri, Amrita Datta, Choi, Doo Chul, Kabaria, Savan, Tran, Alan, Junn, Eunsung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813563/
https://ncbi.nlm.nih.gov/pubmed/26801612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691352
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