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MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression

Nuclear factor E2-related factor 2 (Nrf2) is a key transcription factor that regulates the expression of a number of antioxidant and detoxifying genes that provide cellular protection against various stressors including reactive oxygen species (ROS). Nrf2 activity is tightly regulated by a cytoplasm...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Kabaria, Savan, Choi, Doo Chul, Chaudhuri, Amrita Datta, Jain, Mohit Raja, Li, Hong, Junn, Eunsung
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684759/
https://ncbi.nlm.nih.gov/pubmed/26453926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.09.010
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