Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice

α-Synuclein (α-Syn) is a key pathogenic protein in α-synucleinopathies including Parkinson disease (PD) and Dementia with Lewy Bodies. The aggregation of α-Syn is believed to be deleterious and a critical step leading to neuronal dysfunction and death. One of the factors that may contribute to the i...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuroscience
Hlavní autoři: Zhang, Jie, Jasutkar, Hilary Grosso, Yan, Run, Woo, Jong-Min, Lee, Kang-Woo, Im, Joo-Young, Junn, Eunsung, Iismaa, Siiri E., Mouradian, M. Maral
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024061/
https://ncbi.nlm.nih.gov/pubmed/32502569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.05.047
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky