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DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway

DJ-1, which is linked to recessively inherited Parkinson's disease when mutated, is a multi-functional protein with anti-oxidant and transcription regulatory activities. However, the mechanism(s) through which DJ-1 and the genes it regulates provide neuroprotection is not fully understood. Here...

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Bibliografische gegevens
Hoofdauteurs: Im, Joo-Young, Lee, Kang-Woo, Woo, Jong-Min, Junn, Eunsung, Mouradian, M. Maral
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373246/
https://ncbi.nlm.nih.gov/pubmed/22492997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds131
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