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DJ-1 Protects Against Oxidative Damage by Regulating the Thioredoxin/ASK1 Complex
DJ-1 is a multifunctional protein linked to recessively inherited Parkinson’s disease (PD) due to loss of function mutations. Among its activities is antioxidant property leading to cytoprotection under oxidative stress conditions. A key effector of oxidant-induced cell death is the MAP3 kinase Apop...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883683/ https://ncbi.nlm.nih.gov/pubmed/20385180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2010.04.002 |
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