DJ-1 Protects Against Oxidative Damage by Regulating the Thioredoxin/ASK1 Complex

DJ-1 is a multifunctional protein linked to recessively inherited Parkinson’s disease (PD) due to loss of function mutations. Among its activities is antioxidant property leading to cytoprotection under oxidative stress conditions. A key effector of oxidant-induced cell death is the MAP3 kinase Apop...

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Bibliographic Details
Main Authors: Im, Joo-Young, Lee, Kang-Woo, Junn, Eunsung, Mouradian, M. Maral
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883683/
https://ncbi.nlm.nih.gov/pubmed/20385180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2010.04.002
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