Frequent activation of EGFR in advanced chordomas

BACKGROUND: Chordomas are rare neoplasms, arising from notochordal remnants in the midline skeletal axis, for which the current treatment is limited to surgery and radiotherapy. Recent reports suggest that receptor tyrosine kinases (RTK) might be essential for the survival or proliferation of chordo...

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Detalhes bibliográficos
Main Authors: Dewaele, Barbara, Maggiani, Francesca, Floris, Giuseppe, Ampe, Michèle, Vanspauwen, Vanessa, Wozniak, Agnieszka, Debiec-Rychter, Maria, Sciot, Raf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372284/
https://ncbi.nlm.nih.gov/pubmed/22613809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-1-4
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