Therapeutic Efficacy Assessment of CK6, a Monoclonal KIT Antibody, in a Panel of Gastrointestinal Stromal Tumor Xenograft Models()()

We evaluated the efficacy of CK6, a KIT monoclonal antibody, in a panel of human gastrointestinal stromal tumor (GIST) xenograft models. Nude mice were bilaterally transplanted with human GIST xenografts (four patient derived and two cell line derived), treated for 3 weeks, and grouped as follows: c...

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Veröffentlicht in:Transl Oncol
Hauptverfasser: Van Looy, Thomas, Wozniak, Agnieszka, Floris, Giuseppe, Li, Haifu, Wellens, Jasmien, Vanleeuw, Ulla, Sciot, Raf, Debiec-Rychter, Maria, Schöffski, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415139/
https://ncbi.nlm.nih.gov/pubmed/25926077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2015.02.004
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