Frequent activation of EGFR in advanced chordomas

BACKGROUND: Chordomas are rare neoplasms, arising from notochordal remnants in the midline skeletal axis, for which the current treatment is limited to surgery and radiotherapy. Recent reports suggest that receptor tyrosine kinases (RTK) might be essential for the survival or proliferation of chordo...

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Bibliografiske detaljer
Main Authors: Dewaele, Barbara, Maggiani, Francesca, Floris, Giuseppe, Ampe, Michèle, Vanspauwen, Vanessa, Wozniak, Agnieszka, Debiec-Rychter, Maria, Sciot, Raf
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372284/
https://ncbi.nlm.nih.gov/pubmed/22613809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-1-4
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