Frequent activation of EGFR in advanced chordomas

BACKGROUND: Chordomas are rare neoplasms, arising from notochordal remnants in the midline skeletal axis, for which the current treatment is limited to surgery and radiotherapy. Recent reports suggest that receptor tyrosine kinases (RTK) might be essential for the survival or proliferation of chordo...

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Bibliografske podrobnosti
Main Authors: Dewaele, Barbara, Maggiani, Francesca, Floris, Giuseppe, Ampe, Michèle, Vanspauwen, Vanessa, Wozniak, Agnieszka, Debiec-Rychter, Maria, Sciot, Raf
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372284/
https://ncbi.nlm.nih.gov/pubmed/22613809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-1-4
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