Frequent activation of EGFR in advanced chordomas

BACKGROUND: Chordomas are rare neoplasms, arising from notochordal remnants in the midline skeletal axis, for which the current treatment is limited to surgery and radiotherapy. Recent reports suggest that receptor tyrosine kinases (RTK) might be essential for the survival or proliferation of chordo...

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Bibliografische gegevens
Hoofdauteurs: Dewaele, Barbara, Maggiani, Francesca, Floris, Giuseppe, Ampe, Michèle, Vanspauwen, Vanessa, Wozniak, Agnieszka, Debiec-Rychter, Maria, Sciot, Raf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372284/
https://ncbi.nlm.nih.gov/pubmed/22613809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-1-4
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