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Chimeric antigen receptor (CAR) T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF
The infiltration of suppressive myeloid cells into the tumor microenvironment restrains anti-tumor immunity. However, cytokines may alter the function of myeloid lineage cells to support tumor rejection, regulating the balance between pro- and anti-tumor immunity. In this study, it is shown that eff...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370144/ https://ncbi.nlm.nih.gov/pubmed/22586039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103019 |
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