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NKG2D CAR T cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

Tumor heterogeneity presents a substantial barrier to increasing clinical responses mediated by targeted therapies. Broadening the immune response elicited by treatments that target a single antigen is necessary for the elimination of tumor variants that fail to express the targeted antigen. In this...

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Detalhes bibliográficos
Main Authors: Spear, Paul, Barber, Amorette, Rynda-Apple, Agnieszka, Sentman, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700668/
https://ncbi.nlm.nih.gov/pubmed/23628805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.17
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