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NKG2D CAR T cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors
Tumor heterogeneity presents a substantial barrier to increasing clinical responses mediated by targeted therapies. Broadening the immune response elicited by treatments that target a single antigen is necessary for the elimination of tumor variants that fail to express the targeted antigen. In this...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700668/ https://ncbi.nlm.nih.gov/pubmed/23628805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.17 |
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