IFN Regulatory Factor 8 Represses GM-CSF Expression in T cells to Affect Myeloid Cell Lineage Differentiation

During hematopoiesis, hematopoietic stem cells constantly differentiate into granulocytes and macrophages via a distinct differentiation program that is tightly controlled by myeloid lineage-specific transcription factors. Mice with a null mutation of IFN Regulatory Factor 8 (IRF8) accumulate CD11b(...

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Publicado en:J Immunol
Main Authors: Paschall, Amy V., Zhang, Ruihua, Qi, Chen-Feng, Bardhan, Kankana, Peng, Liang, Lu, Geming, Yang, Jianjun, Merad, Miriam, McGaha, Tracy, Zhou, Gang, Mellor, Andrew, Abrams, Scott I., Morse, Herbert C., Ozato, Keiko, Xiong, Huabao, Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340766/
https://ncbi.nlm.nih.gov/pubmed/25646302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402412
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