A human GM-CSF receptor expressed in transgenic mice stimulates proliferation and differentiation of hemopoietic progenitors to all lineages in response to human GM-CSF.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) mainly stimulates proliferation and maturation of myeloid progenitor cells. Although the signal transduction pathways triggered by GM-CSF receptor (GMR) have been extensively characterized, the roles of GMR signals in differentiation have rem...

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Publicado en:Mol Biol Cell
Main Authors: Nishijima, I, Nakahata, T, Hirabayashi, Y, Inoue, T, Kurata, H, Miyajima, A, Hayashi, N, Iwakura, Y, Arai, K, Yokota, T
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Cell Biology 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7545029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.5.497
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