A human GM-CSF receptor expressed in transgenic mice stimulates proliferation and differentiation of hemopoietic progenitors to all lineages in response to human GM-CSF.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) mainly stimulates proliferation and maturation of myeloid progenitor cells. Although the signal transduction pathways triggered by GM-CSF receptor (GMR) have been extensively characterized, the roles of GMR signals in differentiation have rem...

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Autores principales: Nishijima, I, Nakahata, T, Hirabayashi, Y, Inoue, T, Kurata, H, Miyajima, A, Hayashi, N, Iwakura, Y, Arai, K, Yokota, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC301211/
https://ncbi.nlm.nih.gov/pubmed/7545029
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