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Decitabine and Vorinostat Cooperate to Sensitize Colon Carcinoma Cell to FasL-induced Apoptosis In Vitro and Tumor Suppression In Vivo

The death receptor Fas and its physiological legend, FasL, regulate apoptosis of cancerous cells, thereby functioning as a critical component of the host cancer immunosurveillance system. To evade Fas-mediated apoptosis, cancer cells often down-regulate Fas to acquire an apoptosis-resistant phenotyp...

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Bibliografski detalji
Glavni autori: Yang, Dafeng, Torres, Christina M., Bardhan, Kankana, Zimmerman, Mary, McGaha, Tracy, Liu, Kebin
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398838/
https://ncbi.nlm.nih.gov/pubmed/22461695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103035
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