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NF-κB Directly Regulates Fas Transcription to Modulate Fas-mediated Apoptosis and Tumor Suppression

Fas is a member of the death receptor family. Stimulation of Fas leads to induction of apoptotic signals, such as caspase 8 activation, as well as “non-apoptotic” cellular responses, notably NF-κB activation. Convincing experimental data have identified NF-κB as a critical promoter of cancer develop...

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Detalhes bibliográficos
Main Authors: Liu, Feiyan, Bardhan, Kankana, Yang, Dafeng, Thangaraju, Muthusamy, Ganapathy, Vadivel, Waller, Jennifer L., Liles, Georgia B., Lee, Jeffrey R., Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408167/
https://ncbi.nlm.nih.gov/pubmed/22669972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356279
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