Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

Butyrate, an intestinal microbiota metabolite of dietary fiber, has been shown to exhibit protective effects toward inflammatory diseases such as ulcerative colitis (UC) and inflammation-mediated colorectal cancer. Recent studies have shown that chronic IFN-γ signaling plays an essential role in inf...

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Detalhes bibliográficos
Main Authors: Zimmerman, Mary A., Singh, Nagendra, Martin, Pamela M., Thangaraju, Muthusamy, Ganapathy, Vadivel, Waller, Jennifer L., Shi, Huidong, Robertson, Keith D., Munn, David H., Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378095/
https://ncbi.nlm.nih.gov/pubmed/22517765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00543.2011
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