Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

Mammalian colon harbors trillions of bacteria, yet there is no undue inflammatory response by the host against these bacteria under normal conditions. The bacterial fermentation products acetate, propionate, and butyrate are believed, at least in part, to be responsible for these immunosuppressive e...

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Hlavní autoři: Singh, Nagendra, Thangaraju, Muthusamy, Prasad, Puttur D., Martin, Pamela M., Lambert, Nevin A., Boettger, Thomas, Offermanns, Stefan, Ganapathy, Vadivel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934627/
https://ncbi.nlm.nih.gov/pubmed/20601425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102947
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