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Decitabine and Vorinostat Cooperate to Sensitize Colon Carcinoma Cell to FasL-induced Apoptosis In Vitro and Tumor Suppression In Vivo
The death receptor Fas and its physiological legend, FasL, regulate apoptosis of cancerous cells, thereby functioning as a critical component of the host cancer immunosurveillance system. To evade Fas-mediated apoptosis, cancer cells often down-regulate Fas to acquire an apoptosis-resistant phenotyp...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398838/ https://ncbi.nlm.nih.gov/pubmed/22461695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103035 |
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