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Conformational mutation in human mtDNA detected by direct sequencing of enzymatically amplified DNA.
Restriction enzyme analysis of 241 human mtDNAs revealed polymorphism in the electrophoretic mobility of a fragment corresponding to part of the ND4 gene. Enzymatic amplification and direct sequencing of this fragment demonstrates that a single T--C transition correlates with the faster mobility exh...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1988
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336839/ https://ncbi.nlm.nih.gov/pubmed/2840635 |
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