Conformational mutation in human mtDNA detected by direct sequencing of enzymatically amplified DNA.
Restriction enzyme analysis of 241 human mtDNAs revealed polymorphism in the electrophoretic mobility of a fragment corresponding to part of the ND4 gene. Enzymatic amplification and direct sequencing of this fragment demonstrates that a single T--C transition correlates with the faster mobility exh...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1988
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.13.5945 |
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