Conformational mutation in human mtDNA detected by direct sequencing of enzymatically amplified DNA.

Restriction enzyme analysis of 241 human mtDNAs revealed polymorphism in the electrophoretic mobility of a fragment corresponding to part of the ND4 gene. Enzymatic amplification and direct sequencing of this fragment demonstrates that a single T--C transition correlates with the faster mobility exh...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Vigilant, L, Stoneking, M, Wilson, A C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1988
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.13.5945
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