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Switching between raltegravir resistance pathways analyzed by deep sequencing

OBJECTIVE: Our objective was to analyze the pathways leading to resistance of HIV to the integrase (IN) inhibitor raltegravir (RAL). DESIGN: Three HIV-infected individuals exhibiting RAL resistance pathway switching were characterized using longitudinal analysis of viral samples from plasma. METHODS...

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Detalhes bibliográficos
Main Authors: Mukherjee, Rithun, Jensen, Shane T., Male, Frances, Bittinger, Kyle, Hodinka, Richard L., Miller, Michael D., Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368328/
https://ncbi.nlm.nih.gov/pubmed/21832937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32834b34de
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