Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing

Alternative RNA splicing greatly expands the repertoire of proteins encoded by genomes. Next-generation sequencing (NGS) is attractive for studying alternative splicing because of the efficiency and low cost per base, but short reads typical of NGS only report mRNA fragments containing one or few sp...

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Bibliografske podrobnosti
Main Authors: Ocwieja, Karen E., Sherrill-Mix, Scott, Mukherjee, Rithun, Custers-Allen, Rebecca, David, Patricia, Brown, Michael, Wang, Susana, Link, Darren R., Olson, Jeff, Travers, Kevin, Schadt, Eric, Bushman, Frederic D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488221/
https://ncbi.nlm.nih.gov/pubmed/22923523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks753
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