HIV Sequence Variation Associated With env Antisense Adoptive T-cell Therapy in the hNSG Mouse Model

The first use of lentiviral vectors in humans involved transduction of mature T-cells with an human immunodeficiency virus (HIV)–derived env antisense (envAS) vector to protect cells from HIV infection. In that study, only a minority of the patient T-cell population could be gene-modified, raising t...

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Detalhes bibliográficos
Main Authors: Mukherjee, Rithun, Plesa, Gabriela, Sherrill-Mix, Scott, Richardson, Max W, Riley, James L, Bushman, Frederic D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862538/
https://ncbi.nlm.nih.gov/pubmed/20104212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.316
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