Hepatitis C Virus Transmission Bottlenecks Analyzed by Deep Sequencing

Hepatitis C virus (HCV) replication in infected patients produces large and diverse viral populations, which give rise to drug-resistant and immune escape variants. Here, we analyzed HCV populations during transmission and diversification in longitudinal and cross-sectional samples using 454/Roche p...

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Bibliografiske detaljer
Main Authors: Wang, Gary P., Sherrill-Mix, Scott A., Chang, Kyong-Mi, Quince, Chris, Bushman, Frederic D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876626/
https://ncbi.nlm.nih.gov/pubmed/20375170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02271-09
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