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Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus

The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from the donor to the recipient host. Accurate quantification of the bottleneck size is particularly important for rapidly evolving pathogens such as influenza virus, as narrow bottlene...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sobel Leonard, Ashley, Weissman, Daniel B., Greenbaum, Benjamin, Ghedin, Elodie, Koelle, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487570/
https://ncbi.nlm.nih.gov/pubmed/28468874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00171-17
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