Wird geladen...

In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

Apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer’s disease and has been implicated in the risk for other neurological disorders. The three common ApoE isoforms (ApoE2, E3, and E4) each differ by a single amino acid, with ApoE4 increasing and ApoE2 decreasing the risk of Alz...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wildsmith, Kristin R., Basak, Jacob M., Patterson, Bruce W., Pyatkivskyy, Yuriy, Kim, Jungsu, Yarasheski, Kevin E., Wang, Jennifer X., Mawuenyega, Kwasi G., Jiang, Hong, Parsadanian, Maia, Yoon, Hyejin, Kasten, Tom, Sigurdson, Wendy C., Xiong, Chengjie, Goate, Alison, Holtzman, David M., Bateman, Randall J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366983/
https://ncbi.nlm.nih.gov/pubmed/22675504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038013
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!