The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

Nonalcoholic fatty liver disease (NAFLD) is associated with all features of the metabolic syndrome. Although deposition of excess triglycerides within liver cells, a hallmark of NAFLD, is associated with a loss of insulin sensitivity, it is not clear which cellular abnormality arises first. We have...

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Main Authors: Benhamed, Fadila, Denechaud, Pierre-Damien, Lemoine, Maud, Robichon, Céline, Moldes, Marthe, Bertrand-Michel, Justine, Ratziu, Vlad, Serfaty, Lawrence, Housset, Chantal, Capeau, Jacqueline, Girard, Jean, Guillou, Hervé, Postic, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366390/
https://ncbi.nlm.nih.gov/pubmed/22546860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41636
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