ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

The transcription factor carbohydrate-responsive element–binding protein (ChREBP) has emerged as a central regulator of lipid synthesis in liver because it is required for glucose-induced expression of the glycolytic enzyme liver–pyruvate kinase (L-PK) and acts in synergy with SREBP to induce lipoge...

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Autores principales: Denechaud, Pierre-Damien, Bossard, Pascale, Lobaccaro, Jean-Marc A., Millatt, Lesley, Staels, Bart, Girard, Jean, Postic, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248330/
https://ncbi.nlm.nih.gov/pubmed/18292813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34314
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