Functional analysis of the protein phosphatase activity of PTEN

In vitro, the tumour suppressor PTEN (phosphatase and tensin homologue deleted on chromosome 10) displays intrinsic phosphatase activity towards both protein and lipid substrates. In vivo, the lipid phosphatase activity of PTEN, through which it dephosphorylates the 3 position in the inositol sugar...

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Dettagli Bibliografici
Autori principali: Zhang, Xiaoqun Catherine, Piccini, Antonella, Myers, Michael P., Van Aelst, Linda, Tonks, Nicholas K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365644/
https://ncbi.nlm.nih.gov/pubmed/22413754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120098
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