Functional analysis of the protein phosphatase activity of PTEN

In vitro, the tumour suppressor PTEN (phosphatase and tensin homologue deleted on chromosome 10) displays intrinsic phosphatase activity towards both protein and lipid substrates. In vivo, the lipid phosphatase activity of PTEN, through which it dephosphorylates the 3 position in the inositol sugar...

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Bibliografski detalji
Glavni autori: Zhang, Xiaoqun Catherine, Piccini, Antonella, Myers, Michael P., Van Aelst, Linda, Tonks, Nicholas K.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365644/
https://ncbi.nlm.nih.gov/pubmed/22413754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120098
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