Structure, function and inhibition of the two- and three-domain 4Fe-4S IspG proteins

IspG is a 4Fe4S protein involved in isoprenoid biosynthesis. Most bacterial IspGs contain two domains: a TIM barrel (A) and a 4Fe4S domain (B), but in plants and malaria parasites, there is a large insert domain (A*) whose structure and function are unknown. We show that bacterial IspGs function in...

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Detalhes bibliográficos
Main Authors: Liu, Yi-Liang, Guerra, Francisco, Wang, Ke, Wang, Weixue, Li, Jikun, Huang, Cancan, Zhu, Wei, Houlihan, Kevin, Li, Zhi, Zhang, Yong, Nair, Satish K., Oldfield, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365180/
https://ncbi.nlm.nih.gov/pubmed/22586085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121107109
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