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Atomic resolution structures of discrete stages on the reaction coordinate of the [Fe(4)S(4)] enzyme IspG (GcpE)

IspG is the penultimate enzyme in non-mevalonate biosynthesis of the universal terpene building blocks isopentenyl diphosphate and dimethylallyl diphosphate. Its mechanism of action has been the subject of numerous studies but remained unresolved due to difficulties in identifying distinct reaction...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Main Authors: Quitterer, Felix, Frank, Annika, Wang, Ke, Rao, Guodong, O'Dowd, Bing, Li, Jikun, Guerra, Francisco, Abdel-Azeim, Safwat, Bacher, Adelbert, Eppinger, Jörg, Oldfield, Eric, Groll, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433817/
https://ncbi.nlm.nih.gov/pubmed/25868383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.04.002
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