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Selective Cytotoxicity of Rhodium Metalloinsertors in Mismatch Repair-Deficient Cells()
Mismatches in DNA occur naturally during replication and as a result of endogenous DNA damaging agents, but the mismatch repair (MMR) pathway acts to correct mismatches before subsequent rounds of replication. Rhodium metalloinsertors bind to DNA mismatches with high affinity and specificity and rep...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364161/ https://ncbi.nlm.nih.gov/pubmed/22103240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2015822 |
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