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DNA Mismatch Binding and Antiproliferative Activity of Rhodium Metalloinsertors
Deficiencies in mismatch repair (MMR) are associated with carcinogenesis. Rhodium metalloinsertors bind to DNA base mismatches with high specificity and inhibit cellular proliferation preferentially in MMR-deficient cells versus MMR-proficient cells. A family of chrysenequinone diimine complexes of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747594/ https://ncbi.nlm.nih.gov/pubmed/19175313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8081044 |
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