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AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization That Suppresses Cocaine-Induced Behavior

Cocaine addiction is a major problem affecting all societal and economic classes for which there is no effective therapy. We hypothesized an effective anti-cocaine vaccine could be developed by using an adeno-associated virus (AAV) gene transfer vector as the delivery vehicle to persistently express...

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Bibliographische Detailangaben
Hauptverfasser: Rosenberg, Jonathan B., Hicks, Martin J., De, Bishnu P., Pagovich, Odelya, Frenk, Esther, Janda, Kim D., Wee, Sunmee, Koob, George F., Hackett, Neil R., Kaminsky, Stephen M., Worgall, Stefan, Tignor, Nicole, Mezey, Jason G., Crystal, Ronald G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360503/
https://ncbi.nlm.nih.gov/pubmed/22486244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.178
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